NAD+ is the fuel your cells use to make energy. Your body makes less of it as you get older — and that's usually when the afternoon crash, the brain fog, and the slower recovery start showing up.

NAD+ is a coenzyme found in every living cell. Its job is energy: it carries electrons through the reactions your mitochondria use to turn food into usable fuel, and it's a required ingredient for the enzymes involved in cellular repair. Your body makes its own — and how much you have changes over the course of a lifetime.
One small shot under the skin, on the schedule your doctor sets. Nothing to mix. Nothing to measure.
The shot goes under the skin, so all of it reaches your bloodstream. Pills and powders have to survive your stomach first, and most of the dose is broken down before it ever gets there.
NAD+ is what your cells use to make energy. This gives them more of it — so you're supporting the engine instead of just pushing it harder.

University of Pennsylvania researchers report that falling NAD+ is a hallmark of aging conserved across species — including humans — and that restoring it is among the most actively studied targets in the field.

Using a 7-tesla scanner, researchers measured NAD+ inside the living human brain and watched it fall with every decade — roughly 1.24 micromolar a year, in adults aged 26 to 78. The decline is not theoretical. It is measurable.

A 2025 review of NAD+ metabolism reports that the NR and NMN precursors sold as oral supplements show low stability in human plasma, and that delivering NAD+ directly may behave differently.
Illustrative. Reported decline in tissue NAD+ with age; see Supporting Studies below. No datapoints are plotted and the axis carries no values. Individual levels vary and are not measured or diagnosed by this page.
This isn't about willpower. Your cells are running low on the fuel they need — and a doctor can prescribe it.

Your NAD+ is compounded and dispensed by a state-licensed U.S. pharmacy operating under strict quality standards, with routine testing for sterility, potency and endotoxins.
This matters more for NAD+ than for almost anything else you can buy. The oral NAD+ supplement market is unregulated and inconsistent. A prescription product compounded by a licensed U.S. pharmacy is held to a completely different standard. With Prime Standard Health, you're not guessing what you're putting into your body.
You'll also have ongoing access to your prescribing physician, so treatment can be monitored and adjusted as needed.
Fill out a short medical intake so a licensed physician in your state can evaluate whether NAD+ is appropriate for you.
A state-licensed doctor reviews your information and determines eligibility. If approved, your prescription is issued directly through our pharmacy network.
Once approved, your medication is compounded and shipped directly to your door from a licensed U.S. pharmacy — free and discreet.
No insurance required. No in-person visits. Ongoing physician support included.
Here's the honest difference.
The medicine isn't the expensive part. The clinic is.
Prices published by U.S. clinics as of July 2026 and captured from each clinic's own published rates. NAD+ IV range reflects 500 mg sessions. Prime Standard Health pricing shown is the per-month cost on the 6-month plan.
A coenzyme in every living cell. It's central to how your cells make energy and to the enzymes involved in cellular repair. Your body makes its own, and levels change with age.
Start Free Online VisitNAD+ is found in every cell in your body and is essential for creating cellular energy and maintaining cellular health. NAD+ helps to regulate the body's energy production by stimulating the production of ATP, the body's primary source of energy. In the body, NAD+ is primarily stored in the mitochondria, which are the powerhouse of the cells responsible for producing energy.
Start Free Online VisitThe benefits of NAD+ injections can vary, but generally, the effects of NAD+ injections may start to be noticeable within a few hours to a few days after the first treatment. Some patients report feeling mental clarity and improved mood soon after the injection.
Start Free Online VisitA small injection under the skin (usually the abdomen or thigh) on the schedule your doctor sets. This ensures 100% bioavailability, as it completely bypasses the digestive tract. Detailed dosage instructions from our medical team are included with every order. Your kit includes everything you need.
Start Free Online VisitNo. It arrives ready to use.
Start Free Online VisitNAD+ is naturally produced by your body. Some people experience mild nausea, headaches, or discomfort during initial sessions, especially at higher doses. These typically ease with gradual dosing. Your doctor reviews your health history before prescribing and can adjust your protocol anytime.
Start Free Online VisitMost retail NAD+ is “supplement-grade,” meaning it isn't regulated for exact potency and often loses its “charge” sitting on a hot warehouse shelf. Our NAD+ is Pharmaceutical-Grade (USP). It is compounded in a sterile, licensed U.S. pharmacy upon your order. This ensures you receive a highly stable, 100mg/mL concentration that is biologically active and hasn't been degraded by time or temperature.
Start Free Online VisitYour medication is compounded and dispensed by state-licensed U.S. pharmacies in Prime Standard Health's trusted network and shipped directly to your door with free shipping.
Start Free Online VisitMedication ships in discreet, temperature-controlled packaging with free 2-day delivery. Refills are automatic. Pause or cancel anytime.
Start Free Online VisitNo blood work and no insurance are required to start.
Start Free Online VisitYou're not charged unless a provider approves and prescribes treatment.
Start Free Online VisitEvery source below is linked in full. Reviews are labelled as reviews.
Reports that NAD+ decline in at least some tissues appears to be a conserved feature of aging across species, including humans, and that two MRI-based studies found human brain NAD+ declines by roughly 10–25% between young adulthood and old age.
Cerebral NAD+ declined by an average of 1.24 micromolar per year (p < 0.001).
Reports that NR and NMN show low systemic stability when administered orally, and that direct NAD+ administration may exhibit distinct effects — while noting clinical evidence for direct administration remains limited.
Statements on this website have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease. If you are taking prescription medication, have a medical condition, or are pregnant or nursing, consult your physician before use. Not for children. Results may vary.
NAD⁺ (Nicotinamide Adenine Dinucleotide) is a naturally occurring coenzyme involved in cellular energy and metabolic function. NAD⁺ is not an FDA-approved drug, and its use in supplement or compounded form for wellness, energy, recovery, or anti-aging purposes has not been evaluated or approved by the FDA. NAD⁺ therapy is prescribed only after medical evaluation by a Prime Standard Health affiliated provider when clinically appropriate. Individual results vary based on health status, dosage, and adherence.
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